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Retention mechanisms and dynamic modification of the chiral bonding properties on an 1-acid glycoprotein column pre-treatment of chiral 1-agp column with triethylamine significantly improves detection sensitiv ity of enantiomeric leucotriene antagonist evaluation of the stereoselective metabolism of the chiral analgesic drug etodolac by high-perfor mance liquid chromatography determination of the r, r- and s, s-enantiomers of vamicamide in human serum and urine by high performance liquid chromatography on a chiral-agp column.

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nsaids such as meloxicam, nimesulide, and etodolac show some selectivity for inhibiting cox-2 compared with cox-1.

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